109201-46-9

Basic information

• Product Name: Pyridine, 2-chloro-6-ethyl- (9CI)
• Synonyms: Pyridine, 2-chloro-6-ethyl- (9CI)
• CAS NO: 109201-46-9
• Molecular Formula: C7H8ClN
• Molecular Weight: 141.59812
• Product Categories: PYRIDINE
• Mol File: 109201-46-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyridine, 2-chloro-6-ethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-chloro-6-ethyl- (9CI)(109201-46-9)
• EPA Substance Registry System: Pyridine, 2-chloro-6-ethyl- (9CI)(109201-46-9)

Safety Data

• Hazardous Substances Data: 109201-46-9(Hazardous Substances Data)

Upstream product

• 109-09-1 2-chloropyridine 
• 17200-12-3 lithium 2-(dimethylamino)ethanolate 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 925-90-6 ethylmagnesium bromide 
• 87512-29-6 2-chloro-6-(methylsulfonyl)pyridine 

Relevant articles and documents

Unusual C-6 lithiation of 2-chloropyridine-mediated by BuLi-Me2N(CH2)2OLi. New access to 6-functional-2-chloropyridines and chloro-bis-heterocycles

Formula Presented The reaction of 2-chloropyridine with alkylithium generally results in nucleophilic addition leading to the loss of chlorine atom while exclusive directed ortho metalation is obtained using LDA. Herein it is shown that the BuLi-Me2

IPSO-SUBSTITUTION REACTIONS OF 2- AND 4-SULFONYLPYRIDINES WITH GRIGNARD REAGENTS

The reactions of 2-sulfonylpyridines with Grignard reagents proceeded via an ionic path to give only the corresponding ipso-substitution products, while 4-sulfonylpyridines afforded mainly a mixture of both the substitution and coupling products on treatment with Grignard reagents.