1092075-13-2Relevant academic research and scientific papers
Practical reduction of oxazolines to alcohols
Bernardi, Anna,Ouellet, Stéphane G.,Angelaud, Remy,O'Shea, Paul D.
supporting information; experimental part, p. 6707 - 6708 (2009/04/07)
A two-step, one-pot procedure using methyl chloroformate and lithium borohydride was developed to transform 2-substituted-oxazolines into alcohols. This methodology is compatible with a wide range of substrates including heterocyclic, aromatic, and aliphatic functionalized 2-oxazolines. Best results are obtained with electron-rich and ortho substituted 2-aryl-oxazolines.
