1092102-40-3Relevant academic research and scientific papers
A new approach to the synthesis of polyunsaturated deuterated isoprostanes: Total synthesis of d4-5-epi-8,12-iso-iPF3α-VI and d4-8,12-iso-iPF3α-VI
Chang, Chih-Tsung,Patel, Pranav,Gore, Vivek,Song, Wen-Liang,Lawson, John A.,Powell, William S.,FitzGerald, Garret A.,Rokach, Joshua
scheme or table, p. 6755 - 6758 (2010/06/12)
The total and stereospecific synthesis of d4-5-epi-8,12-iso-iPF3α-VI 55 and d4-8,12-iso-iPF3α-VI 64, EPA-derived all-syn-isoprostanes (iPs), has been accomplished. Because of issues related to volatility and yie
Eicosapentaenoic-acid-derived isoprostanes: Synthesis and discovery of two major isoprostanes
Chang, Chih-Tsung,Patel, Pranav,Kang, Namin,Lawson, John A.,Song, Wen-Liang,Powell, William S.,FitzGerald, Garret A.,Rokach, Joshua
scheme or table, p. 5523 - 5527 (2009/05/30)
The stereospecific synthesis of two all-syn-EPA-derived isoprostanes (iPs), 5-epi-8,12-iso-iPF3α-VI 17 and 8,12-iso-iPF3α-VI 18, has been accomplished. These two synthetic probes have been used to discover and identify their presence in human urine. The eventual quantitative measurement of these two iPs may be a valuable index of oxidative stress in people with eicosapentaenoic acid- (EPA) and docosahexaenoic acid- (DHA) enriched phospholipids.
