1092102-41-4Relevant academic research and scientific papers
Eicosapentaenoic-acid-derived isoprostanes: Synthesis and discovery of two major isoprostanes
Chang, Chih-Tsung,Patel, Pranav,Kang, Namin,Lawson, John A.,Song, Wen-Liang,Powell, William S.,FitzGerald, Garret A.,Rokach, Joshua
, p. 5523 - 5527 (2008)
The stereospecific synthesis of two all-syn-EPA-derived isoprostanes (iPs), 5-epi-8,12-iso-iPF3α-VI 17 and 8,12-iso-iPF3α-VI 18, has been accomplished. These two synthetic probes have been used to discover and identify their presence in human urine. The eventual quantitative measurement of these two iPs may be a valuable index of oxidative stress in people with eicosapentaenoic acid- (EPA) and docosahexaenoic acid- (DHA) enriched phospholipids.
