1092115-04-2Relevant academic research and scientific papers
Chiral Palladacycle Catalysts Generated on a Single-Handed Helical Polymer Skeleton for Asymmetric Arylative Ring Opening of 1,4-Epoxy-1,4-dihydronaphthalene
Yamamoto, Takeshi,Akai, Yuto,Suginome, Michinori
, p. 12785 - 12788 (2014)
Post-polymerization C-H activation of poly(quinoxaline-2,3-diyl)-based helically chiral phosphine ligands (PQXphos) with palladium(II) acetate afforded chiral phosphapalladacycles quantitatively. In situ generated palladacycles exhibited enantioselectivities up to 94 % ee in the palladium-catalyzed asymmetric ring-opening arylation of 1,4-epoxy-1,4-dihydronaphthalenes with arylboronic acids. Polymers with a twist: Poly(quinoxaline-2,3-diyl)-based helically chiral phosphine ligands (PQXphos) have been used to generate chiral phosphapalladacycles. The palladacycles resulted in enantioselectivities of up to 94 % ee in the palladium-catalyzed asymmetric ring-opening arylation of 1,4-epoxy-1,4-dihydronaphthalenes with arylboronic acids.
Platinum(II)-catalyzed asymmetric ring-opening addition of arylboronic acids to oxabenzonorbornadienes
Pan, Xuejing,Huang, Guobao,Long, Yuhua,Zuo, Xiongjun,Xu, Xuan,Gu, Fenglong,Yang, Dingqiao
, p. 187 - 196 (2014/01/17)
A new platinum(II)-catalyzed asymmetric ring-opening addition of arylboronic acids to oxabenzonorbornadienes was developed, which afforded the corresponding cis-2-aryl-1,2-dihydronaphthalen-1-ol products in high yields (up to 97%) with moderate to good enantioselectivities (up to 89% ee) under very mild conditions. The effects of various ligands, catalyst loading, bases, solvents, and temperatures on the yield and enantioselectivity of the reaction were also investigated. The cis configuration of product 2m was confirmed by X-ray diffraction analysis. A potential mechanism for the present catalytic reaction is proposed.
Asymmetric ring-opening reaction of oxabicyclic alkenes with aryl boronic acids catalyzed by P-containing palladacycles
Zhang, Ting-Ke,Mo, Dong-Liang,Dai, Li-Xin,Hou, Xue-Long
supporting information; experimental part, p. 3689 - 3692 (2009/07/09)
(Chemical Equation Presented) The chiral phosphine-containing palladacycle, synthesized easily from H-MOP, showed its high catalytic activity as well as asymmetric induction ability in ring-opening reaction of oxabicyclic alkenes with arylboronic acids, p
