1092115-96-2Relevant academic research and scientific papers
Histone deacetylase inhibitors through click chemistry
Shen, Jie,Woodward, Robert,Kedenburg, James Patrick,Liu, Xianwei,Chen, Min,Fang, Lanyan,Sun, Duxin,Wang, Peng George
experimental part, p. 7417 - 7427 (2009/12/26)
Histone deacetylase inhibitors (HDACi) are a relatively new class of chemotherapy agents. Herein, we report a click-chemistry based approach to the synthesis of HDACi. Fourteen agents were synthesized from the combination of two alkyne and seven azido pre
