1092116-64-7

Basic information

• Product Name: (-)-(2S,3S)-3-benzyl-1-(4-methoxyphenyl)-2-methyl-2-(trifluoromethyl)indoline
• Synonyms: (-)-(2S,3S)-3-benzyl-1-(4-methoxyphenyl)-2-methyl-2-(trifluoromethyl)indoline
• CAS NO: 1092116-64-7
• Molecular Weight: 397.44
• Mol File: 1092116-64-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(2S,3S)-3-benzyl-1-(4-methoxyphenyl)-2-methyl-2-(trifluoromethyl)indoline(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(2S,3S)-3-benzyl-1-(4-methoxyphenyl)-2-methyl-2-(trifluoromethyl)indoline(1092116-64-7)
• EPA Substance Registry System: (-)-(2S,3S)-3-benzyl-1-(4-methoxyphenyl)-2-methyl-2-(trifluoromethyl)indoline(1092116-64-7)

Safety Data

• Hazardous Substances Data: 1092116-64-7(Hazardous Substances Data)

Upstream product

• 117730-45-7 4-methoxy-N-[2,2,2-trifluoro-1-methylethylidene]aniline 
• 835626-64-7 (S)-1-(2-phenylethyl)-2-(p-tolylsulfinyl)benzene 

Relevant articles and documents

Anionic-anionic asymmetric tandem reactions: One-pot synthesis of optically pure fluorinated indolines from 2-p-tolylsulfinyl alkylbenzenes

Chirality switch up: A novel strategy has been developed to give optically pure fluorinated indolines with one or two stereogenic centers (see scheme; AN = nucleophilic addition, PG = protecting group, SNAr = intramolecular nucleophilic aromatic substitution, Tol = tolyl). Almost complete stereoselectivity and mild reaction conditions are the key features of the title reaction. (Chemical Equation Presented)