109221-95-6

Usage

Uses

Used in Organic Synthesis:
BIPHENYL-2-YL-HYDRAZINE HYDROCHLORIDE is used as a chemical building block for the synthesis of complex organic molecules. Its unique structure allows for versatile reactions, making it a valuable component in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Reactions as a Reagent:
In the realm of chemical reactions, BIPHENYL-2-YL-HYDRAZINE HYDROCHLORIDE is utilized as a reagent to facilitate specific transformations. Its presence can enhance the efficiency and selectivity of reactions, contributing to the advancement of synthetic methodologies.
Used in Corrosion Inhibition Applications:
BIPHENYL-2-YL-HYDRAZINE HYDROCHLORIDE is used as a corrosion inhibitor to protect metal surfaces from degradation in various industrial settings. Its effectiveness in inhibiting corrosion has been demonstrated in certain applications, making it a promising candidate for further development in this field.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, BIPHENYL-2-YL-HYDRAZINE HYDROCHLORIDE is used as a key intermediate in the synthesis of new drug compounds. Its potential role in the development of novel therapeutic agents highlights its importance in the ongoing pursuit of medical advancements.

Upstream product

• 90-41-5 2-phenylaniline 

Downstream Products

• 152713-66-1 2-Biphenyl-2-yl-5-butyl-4-(2'-cyano-biphenyl-4-ylmethyl)-2H-pyrazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation

Histone deacetylase inhibitors (HDACi) have emerged as promising therapeutics for the treatment of neurodegeneration, cancer, and rare disorders. Herein, we report the development of a series of spiroindoline-based HDAC6 isoform-selective inhibitors based on the X-ray crystal studies of the hit 6a. We identified compound 6j as the most potent and selective hHDAC6 inhibitor of the series. Biological investigation of compounds 6b, 6h, and 6j demonstrated their antiproliferative activity against several cancer cell lines. Western blotting studies indicated that they were able to increase tubulin acetylation, without significant variation in histone acetylation state, and induced PARP cleavage indicating their apoptotic potential at the molecular level. 6j induced HDAC6-dependent pSTAT3 inhibition.

Oxo carbon-based compounds, a resin composition comprising the same and a filter containing the resin composition

The invention relates to oxo carbon-based compounds, a resin composition comprising the same and a filter containing the resin composition. A novel oxo carbon-based compound is provided, the absorption spectrum in a visible-near infrared region does not h