1092351-10-4 Usage
General Description
8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine is a chemical compound classified as a xanthine derivative. It is a potent and selective antagonist of adenosine A2A receptors, which are found in the central nervous system and play a role in regulating dopamine release. 8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine has been studied for its potential therapeutic applications, particularly in the treatment of neurodegenerative diseases such as Parkinson's. Additionally, it has shown promise in the treatment of various other conditions, including cancer, inflammation, and cardiovascular disease. Its specific chemical structure and pharmacological properties make it a subject of interest for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1092351-10-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,2,3,5 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1092351-10:
(9*1)+(8*0)+(7*9)+(6*2)+(5*3)+(4*5)+(3*1)+(2*1)+(1*0)=124
124 % 10 = 4
So 1092351-10-4 is a valid CAS Registry Number.
1092351-10-4Relevant articles and documents
1-Alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: Development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity
Borrmann, Thomas,Hinz, Sonja,Bertarelli, Daniela C. G.,Li, Wenjin,Florin, Nicole C.,Scheiff, Anja B.,Müller, Christa E.
experimental part, p. 3994 - 4006 (2010/01/06)
A new series of 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines was designed, synthesized, and characterized in radioligand binding and functional assays at A2B adenosine receptors. A2B antagonists with subnanomolar affinity and hig
