1092368-97-2Relevant academic research and scientific papers
Vilsmeier reaction of enaminones: Efficient synthesis of halogenated pyridin-2(1H)-ones
Zhang, Rui,Zhang, Dingyuan,Guo, Yongli,Zhou, Guangyuan,Jiang, Zijiang,Dong, Dewen
experimental part, p. 9504 - 9507 (2009/04/06)
(Chemical Equation Presented) A facile and efficient one-pot synthesis of halogenated pyridin-2(1H)-ones from a series of readily available enaminones under Vilsmeier conditions is described, and a mechanism involving sequential halogenation, formylation, and intramolecular nucleophilic cyclization is proposed.
