1092459-69-2Relevant academic research and scientific papers
Mechanisms of reactions conducted on α-amido-α-aminonitrones, determined based on the structures of their crystalline products and DFT calculations
Trzewik, Bartosz,Seidler, Tomasz,Broclawik, Ewa,Stadnicka, Katarzyna
scheme or table, p. 2220 - 2228 (2011/01/10)
The crystal structures of several compounds obtained from recently synthesised α-amido-α-aminonitrones were determined by X-ray diffraction. The compounds belonged to three different classes: 1,2,5-oxadiazin-4-ones, amidines and dibenzo[d,f][1,3]diazepine
New α-amido-α-aminonitrones as building blocks for constructing heterocyclic systems
Trzewik, Bartosz,Ciez, Dariusz,Hodorowicz, Maciej,Stadnicka, Katarzyna
experimental part, p. 2977 - 2985 (2009/04/05)
New, stable α-amido-α-aminonitrones were obtained in good yields from 3-oxobutyric acid N-pyridin-2-ylamides and nitrosobenzene. The α-amido-α-aminonitrones were then used as new, versatile building blocks to obtaining various heterocycles with both bielectrophilic and binucleophilic reagents. With diiodomethane as reagent, 1,2,5-oxadiazine derivatives were formed, whereas reactions with aromatic 1,2-, 1,3- and 1,4-diamines yielded quinoxaline, quinazoline, perimidine, and dibenzo[d,f][1,3]diazepine derivatives, respectively. Georg Thieme Verlag Stuttgart.
