1092477-78-5

Basic information

• Product Name: Methyl 2-(3-Methylpyridin-2-yl)acetate
• Synonyms: Methyl 2-(3-Methylpyridin-2-yl)acetate
• CAS NO: 1092477-78-5
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.18914
• Mol File: 1092477-78-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: Methyl 2-(3-Methylpyridin-2-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(3-Methylpyridin-2-yl)acetate(1092477-78-5)
• EPA Substance Registry System: Methyl 2-(3-Methylpyridin-2-yl)acetate(1092477-78-5)

Safety Data

• Hazardous Substances Data: 1092477-78-5(Hazardous Substances Data)

Upstream product

• 583-61-9 2,3-Lutidine 
• 616-38-6 carbonic acid dimethyl ester 
• 3430-17-9 2-bromo-3-picoline 
• 1003-73-2 3-picoline-N-oxide 
• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 
• 38203-11-1 (3-methyl-pyridin-2-yl)-acetonitrile 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 127717-19-5 methyl 4-methylpyrazolo<1,5-a>pyridine-3-carboxylate 
• 1092477-23-0 (R)-N'-[3,5-bis(trifluoromethyl)phenyl]-2-(4-methyl-1-piperazinyl)-2-(3-methyl-2-pyridinyl)acetohydrazide 
• 1092477-24-1 (S)-N'-[3,5-bis(trifluoromethyl)phenyl]-2-(4-methyl-1-piperazinyl)-2-(3-methyl-2-pyridinyl)acetohydrazide 
• 1092477-81-0 (+/-)-N'-[3,5-bis(trifluoromethyl)phenyl]-2-(4-methyl-1-piperazinyl)-2-(3-methyl-2-pyridinyl)acetohydrazide 

Relevant articles and documents

Rhodium-catalyzed NH insertion of pyridyl carbenes derived from pyridotriazoles: A general and efficient approach to 2-picolylamines and imidazo[1,5-a]pyridines

A general and efficient NH insertion reaction of rhodium pyridyl carbenes derived from pyridotriazoles was developed. Various NH-containing compounds, including amides, anilines, enamines, and aliphatic amines, smoothly underwent the NH insertion reaction to afford 2-picolylamine derivatives. The developed transformation was further utilized in a facile one-pot synthesis of imidazo[1,5-a]pyridines.

Palladium-catalyzed decarboxylative couplings of 2-(2-Azaaryl)acetates with aryl halides and triflates

Pd-catalyzed decarboxylative cross-couplings of 2-(2-azaaryl)acetates with aryl halides and triflates have been discovered. This reaction is potentially useful for the synthesis of some functionalized pyridines, quinolines, pyrazines, benzoxazoles, and benzothiazoles. Theoretical analysis shows that the nitrogen atom at the 2-position of the heteroaromatics directly coordinates to Pd(II) in the decarboxylation transition state.