1092491-82-1

Basic information

• Product Name: C₂₀H₂₀O₅
• Synonyms: C₂₀H₂₀O₅
• CAS NO: 1092491-82-1
• Molecular Weight: 340.376
• Mol File: 1092491-82-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₀O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₀O₅(1092491-82-1)
• EPA Substance Registry System: C₂₀H₂₀O₅(1092491-82-1)

Safety Data

• Hazardous Substances Data: 1092491-82-1(Hazardous Substances Data)

Upstream product

• 861251-81-2 4-furan-2-yl-4-oxo-but-2-enoic acid ethyl ester 
• 20452-67-9 phenylethylketene 

Relevant articles and documents

Chiral N-heterocyclic carbene-catalyzed formal [4+2] cycloaddition of ketenes with enones: Highly enantioselective synthesis of trans- And cis-δ-lactones

The chiral N-hetrocyclic carbenes (NHC)-catalyzed formal [4+2] cycloaddition of ketones with enones to give δ-lactones was reported. The results show that reaction at 0°C leads to better enantioselectivity and yield, while at -10°C result in slightly better enantioselectivity with lesser yield. It is also noted that the diasterometric ratios and enantiometric excess is improved by a single recrystallization from hexane/2-propanol 9:1. The cis-isomer of δ-lactones could be obtained with high diasteroselectivity and enantioselectivity by the in situ deprotonation-protonation after the NHC-catalyzed cycloaddition. The NHC-catalyzed [4+2] cycloaddition of ketones are possibly initiated by the nucleophilic addition of NHC to ketenes to give triazolium enolates.