1092522-63-8

Basic information

• Product Name: (S)-1-(4-fluorobenzyl)-5-(2-(3,5-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin
• Synonyms: (S)-1-(4-fluorobenzyl)-5-(2-(3,5-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin
• CAS NO: 1092522-63-8
• Molecular Weight: 530.524
• Mol File: 1092522-63-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-1-(4-fluorobenzyl)-5-(2-(3,5-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-fluorobenzyl)-5-(2-(3,5-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin(1092522-63-8)
• EPA Substance Registry System: (S)-1-(4-fluorobenzyl)-5-(2-(3,5-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin(1092522-63-8)

Safety Data

• Hazardous Substances Data: 1092522-63-8(Hazardous Substances Data)

Upstream product

• 1092522-56-9 (S)-5-(2-(3,5-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin 
• 1092522-60-5 (S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin 
• 1092522-53-6 (S)-5-(2-(4-fluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin 
• 132898-96-5 5-chlorosulfonylisatin 
• 2713-34-0 3,5-difluorophenol 
• 459-46-1 4-Fluorobenzyl bromide 

Relevant articles and documents

In vivo imaging used as isatin deriv.

Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.

Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18f]fluoroethylazide

Imaging of programmed cell death (apoptosis) is important in the assessment of therapeutic response in oncology and for diagnosis in cardiac and neurodegenerative disorders. The executioner caspases 3 and 7 ultimately effect cellular death, thus providing