1092536-31-6Relevant articles and documents
Targeting the delivery of glycan-based paclitaxel prodrugs to cancer cells via glucose transporters
Lin, Yih-Shyan,Tungpradit, Rudeewan,Sinchaikul, Supachok,An, Feng-Ming,Liu, Der-Zen,Phutrakul, Suree,Chen, Shui-Tein
experimental part, p. 7428 - 7441 (2009/12/23)
This report describes the synthesis of four novel paclitaxel based prodrugs with glycan conjugation (1-4). Glycans were conjugated using an ester or ether bond as the linker between 2′-paclitaxel and the 2′-glucose or glucuronic acid moiety. These prodrug