1092568-89-2Relevant academic research and scientific papers
Synthesis, evaluation, and mechanism study of new tepotinib derivatives as antiproliferative agents
Zhang, Niu-niu,An, Bai-jiao,Zhou, Yan,Li, Xing-shu,Yan, Ming
, (2019/04/03)
Inspired by the potent inhibition activity of the c-Met (mesenchymal?epithelial transition factor) inhibitor Tepotinib, a series of new Tepotinib derivatives were synthesized and evaluated for their ability to act as antiproliferative agents to find the l
Pyridazinone derivatives
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, (2011/11/12)
Compounds of the formula (I) in which D, R1, R2, R3, R4 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment
THIADIAZINONE DERIVATIVES
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Page/Page column 21-22, (2010/12/29)
Compounds of the formula (I), in which R1, Q and Het have the meanings indicated in Claim 1), are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
2-OXO-3-BENZYLBENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMOURS
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Page/Page column 41, (2010/12/29)
Compounds of the formula (I), in which R1, R2, R3, R3′, R4, R4′, E, E′, E″ and E′″ have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
2-BENZYLPYRIDAZINONE DERIVATIVES AS MET KINASE INHIBITORS
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Page/Page column 25, (2010/12/26)
Compounds of the formula I in which R1, R2, R3, R4′ have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
