1092660-12-2

Basic information

• Product Name: 2-amino-2-phenyl-N-propylacetamide
• Synonyms: 2-amino-2-phenyl-N-propylacetamide
• CAS NO: 1092660-12-2
• Molecular Formula: C₁₁H₁₆N₂O
• Molecular Weight: 192.25754
• Mol File: 1092660-12-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 380.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.055±0.06 g/cm3(Predicted)
• PKA: 15.14±0.46(Predicted)
• CAS DataBase Reference: 2-amino-2-phenyl-N-propylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-2-phenyl-N-propylacetamide(1092660-12-2)
• EPA Substance Registry System: 2-amino-2-phenyl-N-propylacetamide(1092660-12-2)

Safety Data

• Hazardous Substances Data: 1092660-12-2(Hazardous Substances Data)

Usage

General Description

2-amino-2-phenyl-N-propylacetamide is a small organic compound with the chemical formula C11H16N2O. It is commonly known as Prolintane and was originally developed as a central nervous system stimulant and antidepressant. Prolintane acts as a norepinephrine-dopamine reuptake inhibitor, leading to increased levels of these neurotransmitters in the brain and resulting in stimulant effects. It has been used in the treatment of depression and narcolepsy but is now mostly discontinued due to its potential for abuse and dependence. Prolintane is also known for its psychoactive effects and has been used recreationally as a stimulant and euphoriant. It is considered a controlled substance in some countries due to its potential for abuse.

Upstream product

• 1323203-65-1 C₁₆H₂₄N₂O₃ 

Relevant articles and documents

Enantiomeric resolution of α-amino acid derivatives on two diastereomeric chiral stationary phases based on chiral crown ethers incorporating two different chiral units

Two diastereomeric chiral stationary phases (CSPs) were applied to the liquid chromatographic resolution of various racemic a-amino methyl esters, α-amino N,N-diethylamides and α-amino N-propylamides. The CSP incorporating (R)-3,3' -diphenyl-1,1' -binaphtyl and (R,R)-tartaric acid unit as chiral barriers did not show any chiral recognition. In contrast, the CSP incorporating (R)-3,3'-diphenyl-1,1'-binaphtyl and (S,S)-tartaric acid unit as chiral barriers was found to show excellent chiral recognition especially for the two enantiomers of a-amino N-propylamides. Some of a-amino methyl esters and α-amino N,N-diethylamides were also resolved on the CSP incorporating (R)-3,3'-diphenyl-1,1'-binaphtyl and (S,S)-tartaric acid unit. From these results it was concluded that the two chiral units composing the diastereomeric CSPs can show "matched" or "mismatched" effect on the chiral recognition according to their absolute stereochemistry.