1092679-51-0

Basic information

• Product Name: WAY100635
• Synonyms: Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1);WAY-100635 (maleate) N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate
• CAS NO: 1092679-51-0
• Molecular Formula: C29H38N4O6
• Molecular Weight: 538.63522
• Product Categories: Inhibitors
• Mol File: 1092679-51-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Solubility: ≥53.9 mg/mL in DMSO; ≥51.2 mg/mL in EtOH; ≥6.08 mg/mL in H2O with ultrasonic
• CAS DataBase Reference: WAY100635(CAS DataBase Reference)
• NIST Chemistry Reference: WAY100635(1092679-51-0)
• EPA Substance Registry System: WAY100635(1092679-51-0)

Safety Data

• Hazardous Substances Data: 1092679-51-0(Hazardous Substances Data)

Usage

Description

WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and function of 5-HT1A receptors. However, WAY-100635 has also been shown to exhibit agonist activity at dopamine D4 receptors (Kd = 2.4 nM).