109273-57-6

Basic information

• Product Name: 1,2-DIHYDRO-6-(4-METHOXYPHENYL)-4-METHYL-2-OXOPYRIDINE-3-CARBONITRILE
• Synonyms: 1,2-DIHYDRO-6-(4-METHOXYPHENYL)-4-METHYL-2-OXOPYRIDINE-3-CARBONITRILE;SALOR-INT L232939-1EA;6-(4-METHOXYPHENYL)-4-METHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE;2-HYDROXY-6-(4-METHOXYPHENYL)-4-METHYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE
• CAS NO: 109273-57-6
• Molecular Formula: C₁₄H₁₂N₂O₂
• Molecular Weight: 240.26
• Mol File: 109273-57-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-DIHYDRO-6-(4-METHOXYPHENYL)-4-METHYL-2-OXOPYRIDINE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIHYDRO-6-(4-METHOXYPHENYL)-4-METHYL-2-OXOPYRIDINE-3-CARBONITRILE(109273-57-6)
• EPA Substance Registry System: 1,2-DIHYDRO-6-(4-METHOXYPHENYL)-4-METHYL-2-OXOPYRIDINE-3-CARBONITRILE(109273-57-6)

Safety Data

• Hazardous Substances Data: 109273-57-6(Hazardous Substances Data)

Usage

General Description

1,2-Dihydro-6-(4-methoxyphenyl)-4-methyl-2-oxopyridine-3-carbonitrile is a chemical compound with the molecular formula C15H14N2O2. It is a nitrile derivative of a pyridine, and it contains a carbonitrile group, a methyl group, and a methoxyphenyl group. 1,2-DIHYDRO-6-(4-METHOXYPHENYL)-4-METHYL-2-OXOPYRIDINE-3-CARBONITRILE may have applications in pharmaceuticals, as nitrile derivatives can exhibit various biological activities. However, further research is needed to fully understand the potential uses and properties of 1,2-Dihydro-6-(4-methoxyphenyl)-4-methyl-2-oxopyridine-3-carbonitrile.

Upstream product

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Relevant articles and documents

Discovery and structure-activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors

Current treatment for hepatitis C is barely satisfactory, there is an urgent need to develop novel agents for combating hepatitis C virus infection. This study discovered a new class of thieno[2,3-b]pyridine derivatives as HCV inhibitors. First, a hit compound characterized by a thienopyridine core was identified in a cell-based screening of our privileged small molecule library. And then, structure activity relationship study of the hit compound led to the discovery of several potent compounds without obvious cytotoxicity in vitro (12c, EC50 = 3.3 μM, SI >30.3, 12b, EC50 = 3.5 μM, SI >28.6, 10l, EC50 = 3.9 μM, SI >25.6, 12o, EC 50 = 4.5 μM, SI >22.2, respectively). Although the mechanism of them had not been clearly elucidated, our preliminary optimization of this class of compounds had provided us a start point to develop new anti-HCV agents.

SYNTHESIS AND IDENTIFICATION OF ISOMERIC 4(6)-METHYL-6(4)-(SUBSTITUTED PHENYL)-3-CYANO-PYRIDONES

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