109273-74-7

Upstream product

• 140-87-4 Cyanoacetohydrazide 
• 326-06-7 1-Phenyl-4,4,4-trifluorobutane-1,3-dione 

Downstream Products

• 137115-45-8 2,2-Dimethyl-3-(2-methyl-propenyl)-cyclopropanecarboxylic acid (3-cyano-2-oxo-6-phenyl-4-trifluoromethyl-2H-pyridin-1-yl)-amide 
• 327624-56-6 3-(3-cyano-6-phenyl-4-trifluoromethyl-2-pyridon-1-yl)-2-methyl-4(3H)-quinazolinone 
• 137115-56-1 (1R,3S)-3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (3-cyano-2-oxo-6-phenyl-4-trifluoromethyl-2H-pyridin-1-yl)-amide 
• 137115-50-5 (1R,3R)-3-(2,2-Dichloro-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (3-cyano-2-oxo-6-phenyl-4-trifluoromethyl-2H-pyridin-1-yl)-amide 
• 137115-50-5 (1R,3S)-3-(2,2-Dichloro-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (3-cyano-2-oxo-6-phenyl-4-trifluoromethyl-2H-pyridin-1-yl)-amide 

Relevant academic research and scientific papers

Modulators of LXR

Compounds, compositions and methods for modulating the activity of nuclear receptors are provided. In particular, heterocyclic compounds are provided for modulating the activity of nuclear receptors, including liver X receptor (LXR) and orphan nuclear receptors. In certain embodiments, the compounds are N-substituted pyridones.

REACTIONS OF ACYLTHIOSEMICARBAZIDES WITH β-DIKETONES: NOVEL SYNTHESIS OF N-(1-PYRIDYL)THIOUREA DERIVATIVES

The reaction of 1-cyanoacetyl-4-arylthiosemicarbazides with β-diketones was studied as a new route for the synthesis of N-(1-pyridyl)thiourea derivatives.The latter compounds could also be prepared via reaction of the corresponding N-aminopyridines with a

Novel Pyrethroid Insecticides. III. Synthesis of Some N-(1-Pyridyl) Substituted Amides of Cyclopropanecarboxylic Acids

New type pyrethroid amides have been synthesized starting from the corresponding cyclopropanecarboxylic acid chlorides and N-amino-2-pyridone derivatives.