1092803-91-2

Upstream product

• 1092803-47-8 (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-hydroxy-5-methylene-3-(uracil-1-yl)-2-oxabicyclo[2.2.1]heptane 
• 1092803-89-8 C₁₂H₁₆N₂O₅ 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 1092803-94-5 C₃₉H₄₈N₂O₇Si 
• 1092803-92-3 (1R,3R,4R,5R,7S)-7-[2-cyanoethoxy(diisopropylamino)phosphinoxy]-1-(4,4'-dimethoxytrityloxymethyl)-3-(uracil-1-yl)-5-methyl-2-oxa-bicyclo[2.2.1]heptane 
• 1092804-64-2 C₃₉H₄₉N₃O₆Si 

Relevant academic research and scientific papers

Carbocyclic bicyclic nucleic acid analogs

Provided herein are saturated and unsaturated carbocyclic bicyclic nucleosides, oligomeric compounds prepared therefrom and methods of using these oligomeric compounds. The saturated and unsaturated carbocyclic bicyclic nucleosides are useful for enhancin

An exocyclic methylene group acts as a bioisostere of the 2′-oxygen atom in lna

We show for the first time that it is possible to obtain LNA-like (Locked Nucleic Acid 1) binding affinity and biological activity with carbocyclic LNA (cLNA) analogs by replacing the 2′-oxygen atom in LNA with an exocyclic methylene group. Synthesis of t