1092807-33-4Relevant academic research and scientific papers
Chiral bifunctional n-heterocyclic carbenes: Synthesis and application in the aza-Morita-Baylis-Hillman reaction
He, Lin,Zhang, Yan-Rong,Huang, Xue-Liang,Ye, Song
, p. 2825 - 2829 (2008)
A series of chiral bifunctional N-heterocyclic carbene (NHC) precursors with a proximal hydroxy group were smoothly prepared from L-pyroglutamic acid. Promising enantiomeric excesses (up to 44% ee) were achieved for the bifunctional NHC-catalyzed enantioselective aza-Morita-Baylis-Hillman reaction of cyclopent-2-enone with N-tosylphenylmethanimine. Georg Thieme Verlag Stuttgart.
