109281-01-8Relevant academic research and scientific papers
A METHOD FOR THE DETERMINATION OF THE CONFIGURATION OF THE L-PRO-L,D-PHE PSEUDODIPEPTIDE ISOMERS CONTAINING A TRANS-ETHYLENE ISOSTERIC REPLACEMENT OF THE PEPTIDE BOND
Cock, E. De,Marsenille, M. Van,Auwera, L. Van Der,Tourwe, D.,Binst, G. Van
, p. 5403 - 5406 (2007/10/02)
In order to determine the configuration of the diastereoisomers of the dipeptide analogues L-Pro φ(CH=CH, E) L,D-Phe, a method is described involving reduction of the ethylenic bond and cyclization to the lactams.The 1H NMR spectra of the separated isomers allow the assignment of the S,S or R,S configuration.
