109300-32-5

Basic information

• Product Name: N-(5-METHYLISOXAZOL-3-YL)(4-NITROPHENYL)FORMAMIDE
• Synonyms: N-(5-METHYLISOXAZOL-3-YL)(4-NITROPHENYL)FORMAMIDE;N-(5-methyl-1,2-oxazol-3-yl)-4-nitrobenzamide
• CAS NO: 109300-32-5
• Molecular Formula: C₁₁H₉N₃O₄
• Molecular Weight: 247.21
• Mol File: 109300-32-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(5-METHYLISOXAZOL-3-YL)(4-NITROPHENYL)FORMAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-METHYLISOXAZOL-3-YL)(4-NITROPHENYL)FORMAMIDE(109300-32-5)
• EPA Substance Registry System: N-(5-METHYLISOXAZOL-3-YL)(4-NITROPHENYL)FORMAMIDE(109300-32-5)

Safety Data

• Hazardous Substances Data: 109300-32-5(Hazardous Substances Data)

Upstream product

• 1072-67-9 5-methylisoxazol-3-ylamine 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 496843-89-1 4-amino-N-(5-methyl-isoxazol-3-yl)-benzamide 
• 109300-44-9 1-(5-Methyl-isoxazol-3-yl)-5-(4-nitro-phenyl)-1H-tetrazole 
• 109300-38-1 N-(5-Methyl-isoxazol-3-yl)-4-nitro-benzimidoyl chloride 

Relevant articles and documents

Synthesis and antimicrobial evaluation of new phenoxyacetamide derivatives

New N-(5-methylisoxazol-3-yl)-2 or 3 or 4-(phenoxyacetamido)benzamides 6a-t were synthesized and tested for their in vitro antimicrobial activity against gram positive (Staphylococcus aureus ATCC 25923) and gram negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) bacteria as well as fungi (Candida albicans ATCC 10231, Candida tropicalis ATCC 13803 and Cryptococcus neo-formans ATCC 90112). Compounds 6 were devoid of antibacterial as well as antifungal activities at maximum tested concentrations of 50 pg/ml for bacteria and 100 pg/ml for yeast.

Synthesis of Isoxazolyltetrazoles

Isoxazolyltetrazoles 6 and 9 have been synthesized by the reaction of 4-aroylamino- and 3-aroylaminoisoxazoles (4 and 8) with phosphorus pentachloride and azidolysis of the resulting imidoyl chlorides, respectively.The structures of these tetrazoles have