109303-71-1Relevant articles and documents
Novel features of acceptor recognition by β-(1 ← 4)- galactosyltransferase
Kajihara, Yasuhiro,Kodama, Hisashi,Endo, Tsuyoshi,Hashimoto, Hironobu
, p. 361 - 378 (2007/10/03)
In order to understand how β-(1→4)-galactosyltransferase recognizes its glycosyl acceptor, substrate specificities were investigated using synthetic 2-acetamido-2-deoxy-D-glucopyranose (N-acetylglucosamine) derivatives in which the 1-, 2-, 3-, 4-, and 6-p
Enzymic synthesis of HexNAc-containing disaccharide glycosides.
Nilsson
, p. 79 - 83 (2007/10/02)
The following disaccharide glycosides were obtained from the appropriate donor and acceptor glycosides by employing glycosidases from the mollusc Chamelea gallina as catalysts: alpha-D-Galp-OMe (N-acetyl-alpha-D- galactosaminidase), beta-D-GalpNAc-(1----3)-beta-D-Galp-OMe, beta-D-GlcpNAc-(1----3)-beta-D-Galp-OMe, and beta-D-GlcpNAc-(1----6)-alpha-D-Manp-OMe (N-acetyl-beta-D-hexosaminidase). The regioselectivity of the N-acetyl-beta-D-hexosaminidase-catalysed reactions depended on the anomeric configuration of the acceptor. Thus, alpha-D-Galp-OMe gave beta-D-GlcpNAc- (1----6)-alpha-D-Galp-OMe almost exclusively, whereas beta-D-Galp-OMe gave beta-D-GlcpNAc-(1----3)-beta-D-Galp-OMe and beta-D-GlcpNAc-(1----6)-beta-D-Galp-OMe in almost equal amounts. The isolation of the products by chromatography was straightforward.
SYNTHETIC MUCIN FRAGMENTS: METHYL 3-O-(2-ACETAMIDO-2-DEOXY-β-D-GLUCOPYRANOSYL)-β-D-GALACTOPYRANOSYDE AND METHYL 3-O-(2-ACETAMIDO-2-DEOXY-3-O-β-D-GALACTOPYRANOSYL-β-D-GLUCOPYRANOSYL)-β-D-GALACTOPYRANOSIDE
Kohata, Katsunori,Abbas, Saeed A.,Matta, Khushi L.
, p. 127 - 136 (2007/10/02)
Methyl 2,4,6-tri-O-benzyl-β-D-galactopyranoside (5) was obtained crystalline by way of its 3-O-allyl derivative, which was in turn obtained by ring-opening of a presumed 3,4-O-stannylene derivative of methyl β-D-galactopyranoside, followed by benzylation.