1093113-83-7

Basic information

• Product Name: 2-phenyl-8-(piperazin-1-yl)-2,5-dihydro-pyrazolo[4,3-c][1,5]naphthyridin-3-one
• Synonyms: 2-phenyl-8-(piperazin-1-yl)-2,5-dihydro-pyrazolo[4,3-c][1,5]naphthyridin-3-one
• CAS NO: 1093113-83-7
• Molecular Weight: 346.392
• Mol File: 1093113-83-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenyl-8-(piperazin-1-yl)-2,5-dihydro-pyrazolo[4,3-c][1,5]naphthyridin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-8-(piperazin-1-yl)-2,5-dihydro-pyrazolo[4,3-c][1,5]naphthyridin-3-one(1093113-83-7)
• EPA Substance Registry System: 2-phenyl-8-(piperazin-1-yl)-2,5-dihydro-pyrazolo[4,3-c][1,5]naphthyridin-3-one(1093113-83-7)

Safety Data

• Hazardous Substances Data: 1093113-83-7(Hazardous Substances Data)

Upstream product

• 1093114-33-0 ethyl-4-chloro-6-fluoro-[1,5]naphthyridine-3-carboxylate 
• 1093114-31-8 2-(6-fluoro-3-pyridyl)-aminomethylene-malonic acid diethyl ester 
• 1093114-29-4 ethyl-6-fluoro-4-hydroxy-[1,5]naphthyridine-3-carboxylate 
• 110-85-0 piperazine 
• 1093114-35-2 8-fluoro-2-phenyl-2,5-dihydro-pyrazolo[4,3-c][1,5]naphthyridin-3-one 
• 1827-27-6 2-fluoro-5-aminopyridine 

Relevant articles and documents

THERAPEUTIC PYRAZOLONAPHTHYRIDINE DERIVATIVES

The invention provides a novel chemical series of formula (I), as well as methods of use thereof for binding to the benzodiazepine site of the GABAA receptor and negatively modulating the α5 subtype of GABAA, and use of the compound of formula (I) in the manufacture of a medicament for the treatment of GABAA receptor associated disorders. The invention further provides a method of modulation of one or more GABAA subtypes in an animal comprising administering to the animal an effective amount of a compound of formula (I).