1093307-23-3

Basic information

• Product Name: 1-(5-(1-((tetrahydro-2H-pyran-4-yl)methyl)-5-o-tolyl-1H-1,2,3-triazol-4-yl)-1H-indazol-1-yl)ethanone
• Synonyms: 1-(5-(1-((tetrahydro-2H-pyran-4-yl)methyl)-5-o-tolyl-1H-1,2,3-triazol-4-yl)-1H-indazol-1-yl)ethanone
• CAS NO: 1093307-23-3
• Molecular Weight: 415.495
• Mol File: 1093307-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-(1-((tetrahydro-2H-pyran-4-yl)methyl)-5-o-tolyl-1H-1,2,3-triazol-4-yl)-1H-indazol-1-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-(1-((tetrahydro-2H-pyran-4-yl)methyl)-5-o-tolyl-1H-1,2,3-triazol-4-yl)-1H-indazol-1-yl)ethanone(1093307-23-3)
• EPA Substance Registry System: 1-(5-(1-((tetrahydro-2H-pyran-4-yl)methyl)-5-o-tolyl-1H-1,2,3-triazol-4-yl)-1H-indazol-1-yl)ethanone(1093307-23-3)

Safety Data

• Hazardous Substances Data: 1093307-23-3(Hazardous Substances Data)

Upstream product

• 13194-68-8 4-iodo-2-methylaniline 
• 766-47-2 1-ethynyl-2-methylbenzene 
• 1035490-93-7 4-(azidomethyl)tetrahydropyrane 
• 101691-94-5 4-(iodomethyl)tetrahydro-2H-pyran 
• 850363-46-1 1-acetyl-5-iodo-1H-indazole 
• 1093307-22-2 1-((tetrahydro-2H-pyran-4-yl)methyl)-5-o-tolyl-4-(tributylstannyl)-1H-1,2,3-triazole 

Downstream Products

• 1093304-16-5 5-[5-(2-methylphenyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-1,2,3-triazol-4-yl]-1H-indazole 

Relevant articles and documents

5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.