1093348-65-2Relevant academic research and scientific papers
Ethyl 5-[(4-methylphenyl)sulfonyl]-3-oxopentanoate: A bench-stable synthon for ethyl 3-oxopent-4-enoate (Nazarov's Reagent)
Benetti, Simonetta,Carli, Stefano,De Risi, Carmela,Pollini, Gian P.,Veronese, Augusto C.,Zanirato, Vinicio
, p. 2609 - 2612 (2008)
The easily available adducts of sodium p-toluenesulfinate to both acrylonitrile or acrylic acid were efficiently transformed through a two-step, high-yielding sequence into ethyl 5-[(4-methylphenyl)sulfonyl]-3-oxopentanoate, a convenient source for the popular Nazarov's reagent, ethyl 3-oxopent-4-enoate, which could be generated in situ by base-induced β-elimination and used for annulation reactions.
