1093376-83-0

Basic information

• Product Name: bis-(4,6-O-benzylidene-β-D-galactopyranosyl)sulfane
• Synonyms: bis-(4,6-O-benzylidene-β-D-galactopyranosyl)sulfane
• CAS NO: 1093376-83-0
• Molecular Weight: 534.584
• Mol File: 1093376-83-0.mol

Chemical Properties

• CAS DataBase Reference: bis-(4,6-O-benzylidene-β-D-galactopyranosyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: bis-(4,6-O-benzylidene-β-D-galactopyranosyl)sulfane(1093376-83-0)
• EPA Substance Registry System: bis-(4,6-O-benzylidene-β-D-galactopyranosyl)sulfane(1093376-83-0)

Safety Data

• Hazardous Substances Data: 1093376-83-0(Hazardous Substances Data)

Upstream product

• 51555-87-4 β-D-galactopyranosyl-(1→1)-1-thio-β-D-galactopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 

Downstream Products

• 1093376-90-9 bis-[3-O-(3-methoxybenzoyl)-4,6-O-benzylidene-β-D-galactopyranosyl]sulfane 
• 1093376-94-3 bis-(3-O-2-naphthoyl-4,6-O-benzylidene-β-D-galactopyranosyl)sulfane 
• 1093376-85-2 bis-(3-O-benzoyl-4,6-O-benzylidene-β-D-galactopyranosyl)sulfane 
• 1093376-87-4 C₄₇H₄₂O₁₃S 
• 1093376-88-5 C₅₄H₄₆O₁₄S 
• 1093376-84-1 C₃₃H₃₄O₁₁S 
• 1093376-86-3 C₄₀H₃₈O₁₂S 
• 1093376-91-0 bis-[3-O-(4-methylbenzoyl)-4,6-O-benzylidene-β-D-galactopyranosyl]sulfane 
• 1093376-93-2 bis-(3-O-1-naphthoyl-4,6-O-benzylidene-β-D-galactopyranosyl)sulfane 

Relevant articles and documents

Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells

Aromatic 3,3?-diesters of thiodigalactoside were synthesized in a rapid three-step sequence from commercially available thiodigalactoside and evaluated as inhibitors of cancer- and immunity-related galectins. For each of galectins-1, -3, -7, and -9N-terminal domain, aromatic 3,3′-diesters of thiodigalactoside were found to have affinities in the low micromolar range, which represents a 7-70 fold enhancement over thiodigalactoside itself. No significant improvement was found for galectin-8 N-terminal domain. Two of the compounds were selected for testing in cell culture and were shown to have potent antimigratory effects on human PC-3 prostate and human A549 nonsmall-cell lung cancer cells.