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Olanzapine-d8 is a deuterated analog of the atypical antipsychotic drug olanzapine, which is used as an internal standard in liquid chromatography-mass spectrometry (LC/MS) or gas chromatography-mass spectrometry (GC/MS) applications. It is particularly useful in clinical toxicology analysis, therapeutic drug monitoring, and isotope dilution methods. Olanzapine-d8 aids in the accurate quantification and identification of olanzapine in biological samples, ensuring reliable results in various analytical procedures.

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  • 2-methyl-4-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine

    Cas No: 1093380-13-2

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  • 1093380-13-2 Structure
  • Basic information

    1. Product Name: Olanzapine-d8
    2. Synonyms: Olanzapine-d8;Olanzapine-D8 solution
    3. CAS NO:1093380-13-2
    4. Molecular Formula: C17H12D8N4S
    5. Molecular Weight: 320.481794224
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1093380-13-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: 2 °C
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Olanzapine-d8(CAS DataBase Reference)
    10. NIST Chemistry Reference: Olanzapine-d8(1093380-13-2)
    11. EPA Substance Registry System: Olanzapine-d8(1093380-13-2)
  • Safety Data

    1. Hazard Codes: F,Xn
    2. Statements: 11-20/21/22-36
    3. Safety Statements: 16-36/37
    4. RIDADR: UN 1648 3 / PGII
    5. WGK Germany: 2
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 1093380-13-2(Hazardous Substances Data)

1093380-13-2 Usage

Uses

Used in Pharmaceutical Analysis:
Olanzapine-d8 is used as an internal standard for the analysis of olanzapine in pharmaceutical formulations. It helps in the accurate quantification and quality control of the drug in various dosage forms, ensuring the safety and efficacy of the medication.
Used in Clinical Toxicology:
Olanzapine-d8 is used as an internal standard in clinical toxicology analysis to determine the presence and concentration of olanzapine in biological samples, such as blood or urine. This aids in the diagnosis and monitoring of drug toxicity, overdose, or drug interactions.
Used in Therapeutic Drug Monitoring:
Olanzapine-d8 serves as an internal standard in therapeutic drug monitoring, allowing for the precise measurement of olanzapine levels in patients receiving the medication. This helps in optimizing dosage regimens and ensuring the therapeutic effectiveness of the drug while minimizing side effects.
Used in Isotope Dilution Methods:
Olanzapine-d8 is utilized as an internal standard in isotope dilution methods, a technique used for the accurate quantification of trace amounts of substances in complex matrices. This application is particularly relevant in research and development, as well as in the quality control of pharmaceutical products.
Used in Schizophrenia Treatment:
Olanzapine-d8, as a deuterated analog of olanzapine, contributes to the development and optimization of treatments for schizophrenia. Its use as an internal standard in analytical methods helps in the accurate measurement and monitoring of olanzapine levels in patients, ensuring effective treatment and minimizing side effects.
Used in Bipolar Disorder Treatment:
Similarly, olanzapine-d8 plays a role in the treatment of bipolar disorder by supporting the accurate analysis and monitoring of olanzapine levels in patients. This ensures that the medication is administered effectively and safely, managing the symptoms of bipolar disorder.
Used in Psychotic Depression Treatment:
Olanzapine-d8 also supports the treatment of psychotic depression by enabling precise measurement and monitoring of olanzapine levels in patients. This helps in the effective management of the condition and the optimization of treatment strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 1093380-13-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,3,3,8 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1093380-13:
(9*1)+(8*0)+(7*9)+(6*3)+(5*3)+(4*8)+(3*0)+(2*1)+(1*3)=142
142 % 10 = 2
So 1093380-13-2 is a valid CAS Registry Number.

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