1093389-85-5Relevant academic research and scientific papers
Synthesis and biological activity of isoflavone derivatives from chickpea as potent anti-diabetic agents
Li, Pengshou,Shi, Xiaojuan,Wei, Ying,Qin, Lingling,Sun, Wen,Xu, Guangyuan,Xu, Tunhai,Liu, Tonghua
, p. 17016 - 17040 (2015/12/01)
A set of novel isoflavone derivatives from chickpea were synthesized. The structures of derivatives were identified by proton nuclear magnetic resonance (1H-NMR), carbon-13 (13C)-NMR and mass spectrometry (MS) spectral analyses. Thei
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75
Li, Bo-Wen,Zhang, Feng-Hua,Serrao, Erik,Chen, Huan,Sanchez, Tino W.,Yang, Liu-Meng,Neamati, Nouri,Zheng, Yong-Tang,Wang, Hui,Long, Ya-Qiu
, p. 3146 - 3158 (2014/06/09)
HIV integrase (IN) is an essential enzyme for the viral replication. Currently, three IN inhibitors have been approved for treating HIV-1 infection. All three drugs selectively inhibit the strand transfer reaction by chelating a divalent metal ion in the
