1093394-76-3Relevant academic research and scientific papers
O-acetyl oximes as transformable directing groups for Pd-catalyzed C-H bond functionalization
Neufeldt, Sharon R.,Sanford, Melanie S.
supporting information; experimental part, p. 532 - 535 (2010/05/02)
[Chemical equation presented] O-Acetyl oxlmes serve as effective directing groups for Pd-catalyzed sp2 and sp3 C-H functionalization reactions. The C-H functionalization products can be subsequently transformed Into ortho- or β-functionalized ketones, alcohols, amines, and heterocycles.
New metal-free one-pot synthesis of substituted allenes from enones
Tang, Meng,Fan, Chun-An,Zhang, Fu-Min,Tu, Yong-Qiang,Zhang, Wen-Xue,Wang, Ai-Xia
supporting information; experimental part, p. 5585 - 5588 (2009/06/18)
(Chemical Equation Presented) A new metal-free, one-pot synthesis of substituted allenes from enones was discovered for the first time, in which a tertiary amine as a base was found to be an effective promoter in such novel transformations. The present synthetic protocol proceeded readily with high compatibility of sensitive functional groups, and it provides a new efficient way to access a series of synthetically important allenes without the use of metallic reagents or catalysts.
