109345-41-7

Upstream product

• 16652-76-9 ammonium tosylate salt of (2R)-valine benzyl ester 
• 3401-33-0 N^Α-Boc-S-benzyl-L-cysteine N-hydroxysuccinimide ester 
• 46460-17-7 (R)-O-benzyl 2-amino-3-methylbutanoate 
• 55478-08-5 N-[(1,1-dimethylethoxy)-carbonyl]-S-(phenylmethyl)-L-cysteine methyl Ester 

Downstream Products

• 123872-88-8 (R)-2-((R)-2-Amino-3-benzylsulfanyl-propionylamino)-3-methyl-butyric acid benzyl ester; hydrochloride 
• 69644-78-6 bis[Aad(-Cys-D-Val)] 
• 79761-05-0 N-benzyloxycarbonyl-α-benzyl-δ-(L-α-aminoadipoyl)-S-benzyl-L-cysteinyl-D-valine benzyl ester 

Relevant academic research and scientific papers

A Search for Peptide Ligase: Cosolvent-Mediated Conversion of Proteases to Esterases for Irreversible Synthesis of Peptides

Serine and cysteine proteases (trypsin, chymotrypsin, papain, subtilisin) in the presence of certain concentrations of water-miscible organic solvents express no amidase activities.The esterase activities, however, remain significant.These modified enzyme

EFFICIENT ROUTES TO THE ARNSTEINS'S TRIPEPTIDE δ-(L-α-AMINOADIPYL)-L-CYSTEINYL-D-VALINE (LLD ACV) FROM THE OXIDATION PRODUCTS OF L-LYSINE DERIVATIVES

Two efficient syntheses of the linear tripeptide precursor of penam and cephem antibiotics are presented.The routes are characterised by the use of L-lysine derivatives, Z-L-Lys(Z)-OH and H-L-Lys(Z)-OH as starting materials.By the permanganate oxidation t