1093625-97-8

Basic information

• Product Name: N-{4-methyl-3-[2-(6-methylamino-pyrimidin-4-yl)-2H-[1,2,4]triazol-3-ylamino]-phenyl}-3-trifluoromethyl-benzamide
• Synonyms: N-{4-methyl-3-[2-(6-methylamino-pyrimidin-4-yl)-2H-[1,2,4]triazol-3-ylamino]-phenyl}-3-trifluoromethyl-benzamide
• CAS NO: 1093625-97-8
• Molecular Weight: 468.441
• Mol File: 1093625-97-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{4-methyl-3-[2-(6-methylamino-pyrimidin-4-yl)-2H-[1,2,4]triazol-3-ylamino]-phenyl}-3-trifluoromethyl-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-methyl-3-[2-(6-methylamino-pyrimidin-4-yl)-2H-[1,2,4]triazol-3-ylamino]-phenyl}-3-trifluoromethyl-benzamide(1093625-97-8)
• EPA Substance Registry System: N-{4-methyl-3-[2-(6-methylamino-pyrimidin-4-yl)-2H-[1,2,4]triazol-3-ylamino]-phenyl}-3-trifluoromethyl-benzamide(1093625-97-8)

Safety Data

• Hazardous Substances Data: 1093625-97-8(Hazardous Substances Data)

Upstream product

• 1093626-01-7 4-methyl-N₃-[2-(6-methylamino-pyrimidin-4-yl)-2H-[1,2,4]triazol-3-yl]-benzene-1,3-diamine 
• 454-92-2 3-(trifluoromethyl)benzoic acid 

Relevant articles and documents

PROTEIN KINASE INHIBITORS AND METHODS FOR USING THEREOF

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of Alk, Abl, Aurora-A, B-Raf, C-Raf, Bcr-Abl, BRK, Blk, Bmx, BTK, C-Kit, CSK, C-Src, EphB1, EphB2, EphB4, FLT1, Fms, Flt3, Fyn, FRK3, JAK2, KDR, Lck, Lyn, PDGFRα, PDGFRβ, PKCα, SAPK2α, Src, SIK, Syk, Tie2 and TrkB kinases.