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1093881-58-3

(3S)-4-(4-methoxybenzyl)-3-methylmorpholine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1093881-58-3 Structure

  • Basic information

    1. Product Name: (3S)-4-(4-methoxybenzyl)-3-methylmorpholine
    2. Synonyms: (3S)-4-(4-methoxybenzyl)-3-methylmorpholine
    3. CAS NO:1093881-58-3
    4. Molecular Formula:
    5. Molecular Weight: 221.299
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1093881-58-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (3S)-4-(4-methoxybenzyl)-3-methylmorpholine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3S)-4-(4-methoxybenzyl)-3-methylmorpholine(1093881-58-3)
    11. EPA Substance Registry System: (3S)-4-(4-methoxybenzyl)-3-methylmorpholine(1093881-58-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1093881-58-3(Hazardous Substances Data)

1093881-58-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1093881-58-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,3,8,8 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1093881-58:
(9*1)+(8*0)+(7*9)+(6*3)+(5*8)+(4*8)+(3*1)+(2*5)+(1*8)=183
183 % 10 = 3
So 1093881-58-3 is a valid CAS Registry Number.

1093881-58-3Downstream Products

1093881-58-3Relevant articles and documents

Discovery of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally-active GSK-3β inhibitors for Alzheimer's disease

Fukunaga, Kenji,Sakai, Daiki,Watanabe, Kazutoshi,Nakayama, Kazuki,Kohara, Toshiyuki,Tanaka, Hiroshi,Sunada, Shinji,Nabeno, Mika,Okamoto, Masako,Saito, Ken-Ichi,Eguchi, Jun-Ichi,Mori, Akiko,Tanaka, Shinji,Inazawa, Keiko,Horikawa, Takashi

, p. 1086 - 1091 (2015/02/19)

We herein describe the results of further evolution of GSK-3β inhibitors for Alzheimer's disease from our promising compounds with in vivo tau phosphorylation inhibitory activity by oral administration. Introduction of a low alkyl group instead of the phenyl group at the 3-position of the morpholine moiety aiming to improve pharmacokinetic profiles resulted in potent low molecular weight GSK-3β inhibitors with good in vitro pharmacokinetic profiles, which also showed in vivo tau phosphorylation inhibitory activity by oral administration. Effect of the stereochemistry of the alkyl moiety is also discussed using docking models.

INHIBITORS OF JANUS KINASES

-

, (2009/01/23)

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

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