1093942-95-0Relevant articles and documents
Palladium-mediated [2+1] cycloaddition of norbornene derivatives with ynamides
Clavier, Herve,Lepronier, Aymeric,Bengobesse-Mintsa, Nathalie,Gatineau, David,Pellissier, Helene,Giordano, Laurent,Tenaglia, Alphonse,Buono, Gerard
, p. 403 - 408 (2013)
An efficient palladium-catalyzed [2+1] cycloaddition between ynamides and norbornenes or norbornadienes is reported. Both phosphapalladacycles and palladium/secondary phosphine oxide catalytic systems were found to be competent for the transformation allowing the preparation of aminomethylenecyclopropanes. The reaction showed general applicability to various functionalized bicyclo[2.2.1]hept-2-enes and ynamides. A chiral phosphapalladacycle was tested to carry out this transformation in an enantioselective fashion.
Pd/Cu-Catalyzed tandem head-to-tail dimerization/cycloisomerization of terminal ynamides for the synthesis of 5-vinyloxazolones
Tang, Luning,Huang, Hai,Xi, Yang,He, Guangke,Zhu, Hongjun
, p. 2923 - 2930 (2017/04/11)
An attractive and novel methodology involving Pd/Cu-catalyzed tandem head-to-tail dimerization/cycloisomerization of terminal ynamides for the synthesis of 3,5-disubstituted oxazolones was developed. Under Pd(PPh3)2Cl2/CuI
Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: Beyond the Dimroth rearrangement
Ferrini, Serena,Chandanshive, Jay Zumbar,Lena, Stefano,Comes Franchini, Mauro,Giannini, Giuseppe,Tafi, Andrea,Taddei, Maurizio
, p. 2562 - 2572 (2015/03/18)
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collections of peptidomimetics or biologically active compounds based on the triazole scaffold. However, its chemistry may be influenced by the possibility of under
