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N-CBZ-4,4'-BIPIPERIDINE, also known as N-carbobenzoxy-4,4'-bipiperidine, is an organic compound that serves as a crucial intermediate in the synthesis of various biologically active molecules. It is characterized by its unique molecular structure, which features a benzyloxycarbonyl (CBZ) group attached to a bipiperidine framework. This structure endows N-CBZ-4,4'-BIPIPERIDINE with specific reactivity and functional group compatibility, making it a valuable building block in the development of pharmaceuticals and other bioactive compounds.

109397-72-0

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109397-72-0 Usage

Uses

Used in Pharmaceutical Industry:
N-CBZ-4,4'-BIPIPERIDINE is used as a reactant in the preparation of guanidine compounds, specifically as VAP-1 inhibitors. VAP-1 (vascular adhesion protein-1) is a surface enzyme that plays a role in various pathological conditions, including inflammation, cancer, and autoimmune diseases. By inhibiting VAP-1, these guanidine compounds can potentially modulate immune responses and exhibit therapeutic effects in treating these conditions.
As a key intermediate in the synthesis of bioactive molecules, N-CBZ-4,4'-BIPIPERIDINE can also be utilized in the development of other pharmaceutical agents targeting different therapeutic areas. Its unique structure allows for further functionalization and modification, enabling the creation of novel compounds with diverse biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 109397-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,3,9 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 109397-72:
(8*1)+(7*0)+(6*9)+(5*3)+(4*9)+(3*7)+(2*7)+(1*2)=150
150 % 10 = 0
So 109397-72-0 is a valid CAS Registry Number.

109397-72-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name benzyl 4-piperidin-4-ylpiperidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names N-Cbz-4,4'-bipiperidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109397-72-0 SDS

109397-72-0Relevant academic research and scientific papers

17 Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases

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Page 22-23, (2008/06/13)

In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17β-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of

Modified aminoacids, pharmaceuticals containing these compounds and method for their production

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Example A21a), (2008/06/13)

The present invention relates to modified amino acids of general formula wherein A, Z, X, n, m, R, R2, R3, R4and R11are defined as in claims 1 to 5, their tautomers, their diastereomers, their enantiomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them as well as their use for the production and purification of antibodies and as labelled compounds in RIA- and ELISA assays and as diagnostic or analytical aids in neurotransmitter research.

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