Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1093977-02-6

N,N-dibenzyl-2-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1093977-02-6 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1093977-02-6 Structure

  • Basic information

    1. Product Name: N,N-dibenzyl-2-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}acetamide
    2. Synonyms:
    3. CAS NO:1093977-02-6
    4. Molecular Formula:
    5. Molecular Weight: 492.58
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1093977-02-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N,N-dibenzyl-2-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N,N-dibenzyl-2-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}acetamide(1093977-02-6)
    11. EPA Substance Registry System: N,N-dibenzyl-2-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}acetamide(1093977-02-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1093977-02-6(Hazardous Substances Data)

1093977-02-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1093977-02-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,3,9,7 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1093977-02:
(9*1)+(8*0)+(7*9)+(6*3)+(5*9)+(4*7)+(3*7)+(2*0)+(1*2)=186
186 % 10 = 6
So 1093977-02-6 is a valid CAS Registry Number.

1093977-02-6Downstream Products

1093977-02-6Relevant articles and documents

Triazoloamides as potent γ-secretase modulators with reduced hERG liability

Fischer, Christian,Zultanski, Susan L.,Zhou, Hua,Methot, Joey L.,Shah, Sanjiv,Nuthall, Hugh,Hughes, Bethany L.,Smotrov, Nadja,Hill, Armetta,Szewczak, Alexander A.,Moxham, Christopher M.,Bays, Nathan,Middleton, Richard E.,Munoz, Benito,Shearman, Mark S.

, p. 3140 - 3146 (2012/06/04)

Synthesis and SAR studies of novel aryl triazoles as gamma secretase modulators (GSMs) are presented in this communication. Starting from our aryl triazole leads, optimization studies were continued and the series progressed towards novel amides and lactams. Triazole 57 was identified as the most potent analog in this series, displaying single-digit nanomolar Aβ42 IC 50 in cell-based assays and reduced affinity for the hERG channel.

TRIAZOLE DERIVATIVES FOR TREATING ALZHEIMER'S DISEASE AND RELATED CONDITIONS

-

Page/Page column 36-37; 45; 70, (2009/01/23)

Compounds of formula I: Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain, in particular Alzheimer's disease.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1093977-02-6