1094-63-9

Basic information

• Product Name: 1,3-dimethyl-8-(4-nitrophenyl)-3,7-dihydro-1H-purine-2,6-dione
• Synonyms: 1,3-Dimethyl-8-(4-nitrophenyl)-3,7-dihydro-1H-purine-2,6-dione; 1H-purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-(4-nitrophenyl)-
• CAS NO: 1094-63-9
• Molecular Formula: C₁₃H₁₁N₅O₄
• Molecular Weight: 301.2575
• Mol File: 1094-63-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 597.1°C at 760 mmHg
• Flash Point: 314.9°C
• Density: 1.506g/cm³
• Vapor Pressure: 3.2E-14mmHg at 25°C
• Refractive Index: 1.665
• CAS DataBase Reference: 1,3-dimethyl-8-(4-nitrophenyl)-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethyl-8-(4-nitrophenyl)-3,7-dihydro-1H-purine-2,6-dione(1094-63-9)
• EPA Substance Registry System: 1,3-dimethyl-8-(4-nitrophenyl)-3,7-dihydro-1H-purine-2,6-dione(1094-63-9)

Safety Data

• Hazardous Substances Data: 1094-63-9(Hazardous Substances Data)

Usage

General Description

1,3-dimethyl-8-(4-nitrophenyl)-3,7-dihydro-1H-purine-2,6-dione, also known as caffeine, is a chemical compound that is commonly found in coffee, tea, and energy drinks. It is a central nervous system stimulant and acts as a mild diuretic. Caffeine is known for its ability to improve mental alertness, reduce fatigue, and enhance physical performance. It is also used in the treatment of headaches, migraines, and respiratory disorders. However, excessive consumption of caffeine can lead to adverse effects such as insomnia, restlessness, and increased heart rate.

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Relevant articles and documents

Smooth Metal-Free Photoinduced Preparation of Valuable 8-Arylxanthines

A set of 8-arylxanthines was prepared under metal-free conditions and in aqueous solvents from arylazo sulfones and caffeine or theophylline. Notably, the process took place by simply exposing the reaction vessel to visible or solar light, and unreacted xanthine could be easily recovered during the purification step.

A mild method for the preparation of 8-substituted xanthines from 5,6- diaminouracils

The Schiff base derivatives (3), prepared from the respective 5,6- diaminouracil (1) and aldehydes can be mildly oxidatively cyclized with m- CPBA in MeCN to afford C-8 substituted xanthines (6).

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: Potent Water-Soluble Antagonistst for A1- and A2-Adenosine Receptors

A series of 8-(substituted phenyl) derivatives of Theophylline and other 1,3-dialkylxanthines were evaluated for potency and selectivity as antagonists at A1- and A2-adenosine receptors in brain tissue.Theophylline has a similar pote