1094102-82-5 Usage
Uses
Used in Pharmaceutical Research:
(S)-Naproxen-d3 is used as a research tool for studying the pharmacokinetics and metabolism of (S)-Naproxen in the body. The presence of deuterium atoms allows for more precise measurements and analysis of the drug's distribution and metabolic pathways.
Used in Clinical Studies:
(S)-Naproxen-d3 is used as a labeled compound in clinical settings to track the drug's metabolism and distribution, providing valuable information for understanding the drug's effectiveness and potential side effects.
Used in Drug Development:
(S)-Naproxen-d3 can be employed in the development of new drugs with improved pharmacokinetic properties, by studying its behavior in comparison to the non-deuterated form of the drug.
Used in Metabolomics:
(S)-Naproxen-d3 is used as an internal standard in metabolomics studies, helping to improve the accuracy and reliability of measurements in the analysis of biological samples.
Used in Analytical Chemistry:
(S)-Naproxen-d3 can be utilized as a reference compound in analytical chemistry, aiding in the development and validation of new methods for the detection and quantification of (S)-Naproxen and its metabolites.
Check Digit Verification of cas no
The CAS Registry Mumber 1094102-82-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,4,1,0 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1094102-82:
(9*1)+(8*0)+(7*9)+(6*4)+(5*1)+(4*0)+(3*2)+(2*8)+(1*2)=125
125 % 10 = 5
So 1094102-82-5 is a valid CAS Registry Number.
1094102-82-5Relevant articles and documents
Synthesis of deuterated naproxens
Gannett, Peter M.,Miller, Laura,Daft, Jonathan,Locuson, Charles,Tracy, Timothy S.
, p. 1272 - 1275 (2007)
A general scheme for the synthesis of (S)-6-methoxy-2-propanoic acid (naproxen) deuterated on the naphthyl ring, methoxy group, or both, is described. The resulting labeled naproxen derivatives are useful probes for examining atypical kinetics displayed by cytochrome P450 2C9. Copyright
NAPTHYLENE INHIBITORS OF CYCLOOXYGENASE
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Page/Page column 39-40, (2010/11/18)
The present invention relates to new napthylene inhibitors of cyclooxygenase activity, pharmaceutical compositions thereof, and methods of use thereof.
PREPARATION AND UTILITY OF SUBSTITUTED CARBOXYLIC ACID COMPOUNDS
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Page/Page column 59, (2008/06/13)
The present disclosure is directed to modulators of cyclooxygenase (COX) enzymes and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of the s
