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109434-22-2

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109434-22-2 Usage

Chemical Properties

Colourless oil, stench!

Uses

1-Isocyano-2-methoxy-2-methyl-propane is a ligand used in Technetium (99mTc) sestamibi for nuclear medicine imaging.

Check Digit Verification of cas no

The CAS Registry Mumber 109434-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,4,3 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 109434-22:
(8*1)+(7*0)+(6*9)+(5*4)+(4*3)+(3*4)+(2*2)+(1*2)=112
112 % 10 = 2
So 109434-22-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO/c1-6(2,8-4)5-7-3/h5H2,1-2,4H3

109434-22-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-isocyano-2-methoxy-2-methylpropane

1.2 Other means of identification

Product number -
Other names 2-methoxyisobutylisocyanide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109434-22-2 SDS

109434-22-2Relevant articles and documents

Preparation and biodistribution of novel 99mTc(CO) 3-CNR complexes for myocardial imaging

Hao, Guiyang,Zang, Jianying,Liu, Boli

, p. 13 - 18 (2007)

We evaluated lipophilicity and biodistribution of a series of 99mTc(CO)3-ether isonitrile complexes to determine whether different lipophilicity and structure of isonitrile ligands would improve the imaging properties of the radiopharmaceutical for the heart. Novel 99mTc(CO)3-MIBI analogs were prepared and analyzed by radio-HPLC, and their lipophilicity was determined. These new complexes could be bi- or tri-substituted in specified pH conditions like 99mTc(CO) 3-MIBI. These new complexes exhibited low liver, lungs and blood uptake compared with [99mTc(CO)3(MIBI)3] + though their heart uptake was not so high. Among these complexes, [99mTc(CO)3(EPI)2(OH2)]+ showed higher target to non-target ratios at 5 and 30 min post-injection than that of [99mTc(CO)3(MIBI)3]+. Copyright

METHODS FOR PREPARING 2-METHOXYISOBUTYLISONITRILE AND TETRAKIS(2-METHOXYISOBUTYLISONITRILE)COPPER(I) TETRAFLUOROBORATE

-

Page/Page column 9; 11-12, (2008/06/13)

The present invention relates to new synthetic methods for preparing 2-methoxyisobutylisonitrile and metal isonitrile complexes, such as tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluroroborate, which are used in the preparation of technetium (99mTc) Sestamibi, and novel intermediate compounds useful in such methods.

Ether isonitriles and radiolabeled complexes thereof

-

, (2008/06/13)

Ether-substituted isonitriles, Tc99m complexes thereof, and processes for myocardial tissue radioimaging using the Tc99m complexes.

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