1094347-64-4

Basic information

• Product Name: 3-ethyl-4-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE)
• Synonyms: 3-ethyl-4-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE);3-ethyl-4-methyl-1H-pyrazole-5-carboxylic acid
• CAS NO: 1094347-64-4
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.1665
• Mol File: 1094347-64-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-ethyl-4-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethyl-4-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE)(1094347-64-4)
• EPA Substance Registry System: 3-ethyl-4-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE)(1094347-64-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1094347-64-4(Hazardous Substances Data)

Usage

General Description

3-Ethyl-4-methyl-1H-pyrazole-5-carboxylic acid is a chemical compound with the molecular formula C8H10N2O2. It is a pyrazole derivative, which is a class of organic compounds containing a five-membered ring with two nitrogen atoms. This particular compound has an ethyl and methyl group attached to the pyrazole ring, along with a carboxylic acid functional group. It is commonly used in pharmaceutical research and drug synthesis due to its potential as a building block for various biologically active compounds. Additionally, its molecular structure and properties make it a valuable tool for the study of pyrazole-based drugs and their interactions with biological systems.

Upstream product

• 107-87-9 2-Pentanone 

Downstream Products

• 1085453-50-4 5-ethyl-4-methyl-1-(4-methylbenzyl)-1H-pyrazole-3-carboxylic acid 
• 1085453-49-1 methyl 5-ethyl-4-methyl-1H-pyrazole-3-carboxylate hydrochloride 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRAZOLE DERIVATIVES

The invention provides a process for manufacturing 5-ethyl-4-methyl-N-[4-[(2S) morpholin-2-yl]phenyl]-1H-pyrazole-3-carboxamide (Formula I), or a pharmaceutically acceptable salt thereof, on an industrial scale, Formula (I), comprising a one-pot process for manufacturing 5-ethyl-4-methyl-lH-pyrazole-3- carboxylic acid (1).

Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a

A series of 5-alkyl pyrazole-3-carboxylic acids were prepared and found to act as potent and selective agonists of the human GPCR, GPR109a, the high affinity nicotinic acid receptor. No activity was observed at the highly homologous low affinity niacin receptor, GPR109b. A further series of 4-fluoro-5-alkyl pyrazole-3-carboxylic acids were shown to display similar potency. One example from the series was shown to have improved properties in vivo compared to niacin.