1094570-19-0

Basic information

• Product Name: (1R,2R,3S,4R)-dimethyl 4-(4-chlorophenyl)-2-hydroxycyclohexane-1,3-dicarboxylate
• Synonyms: (1R,2R,3S,4R)-dimethyl 4-(4-chlorophenyl)-2-hydroxycyclohexane-1,3-dicarboxylate
• CAS NO: 1094570-19-0
• Molecular Weight: 326.777
• Mol File: 1094570-19-0.mol

Chemical Properties

• CAS DataBase Reference: (1R,2R,3S,4R)-dimethyl 4-(4-chlorophenyl)-2-hydroxycyclohexane-1,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,4R)-dimethyl 4-(4-chlorophenyl)-2-hydroxycyclohexane-1,3-dicarboxylate(1094570-19-0)
• EPA Substance Registry System: (1R,2R,3S,4R)-dimethyl 4-(4-chlorophenyl)-2-hydroxycyclohexane-1,3-dicarboxylate(1094570-19-0)

Safety Data

• Hazardous Substances Data: 1094570-19-0(Hazardous Substances Data)

Upstream product

• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 1075-77-0 (E)-4-chlorocinnamic aldehyde 

Relevant articles and documents

Catalytic batch and continuous flow production of highly enantioenriched cyclohexane derivatives with polymer-supported diarylprolinol silyl ethers

Diarylprolinol silyl ethers immobilized onto polystyrene have been employed as catalysts in the enantioselective domino Michael-Knoevenagel reaction of dimethyl 3-oxoglutarate and 3-substituted acrolein derivatives, including aliphatic ones. The best catalyst allows the preparation of highly functionalized cyclohexane derivatives in a straightforward and efficient manner, both under batch and continuous flow conditions. Georg Thieme Verlag Stuttgart.

Diphenylprolinol silyl ether catalysis in an asymmetric formal carbo [3 + 3] cycloaddition reaction via a domino michael/knoevenagel condensation

Diphenylprolinol silyl ether was found to catalyze the formal carbo [3 + 3] cycloaddition reaction through the domino reaction via the Michael reaction, followed by Knoevenagel condensation of the α, β-unsaturated aldehyde and dimethyl 3-oxopentanedioate,