109458-85-7Relevant articles and documents
New routes to ss-cycloalkylalanine derivatives using serine-derived organozinc reagents
Carrillo-Marquez, Tomas,Caggiano, Lorenzo,Jackson, Richard F. W.,Grabowska, Urszula,Rae, Alastair,Tozer, Matthew J.
, p. 4117 - 4123 (2005)
Two distinct routes to β-cycloalkylalanine derivatives have been developed. The first route employs the reaction of the iodoalanine-derived zinc-copper reagent 2 with cycloalk-l-en-3-yl phosphates, and the second uses the palladium-catalysed coupling of t
TRIAZOLYL DERIVATIVES AS SYK INHIBITORS
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Page/Page column 104, (2014/04/17)
Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.
Mild two-step process for the transition-metal-free synthesis of carbon-carbon bonds from allylic alcohols/ethers and grignard reagents
Han, Xinping,Zhang, Yanhua,Wu, Jimmy
supporting information; experimental part, p. 4104 - 4106 (2010/05/15)
Chemical Equation Represented A mild two-step process for the regioselective, transition-metal-free preparation of carbon-carbon bonds from allylic alcohols/ethers and Grignard reagents is described. This process obviates the need for the harsh deprotecti