1094601-70-3Relevant academic research and scientific papers
Synthesis and properties of siRNAs containing 5′-amino-2′,5′-dideoxy-2′α-fluororibonucleosides
Ueno, Yoshihito,Hirai, Miki,Yoshikawa, Kayo,Kitamura, Yoshiaki,Hirata, Yoko,Kiuchi, Kazutoshi,Kitade, Yukio
, p. 11328 - 11334 (2008)
Short interfering RNAs (siRNAs) containing P3′→N5′ phosphoramidate linkages were successfully synthesized by introducing 2′-deoxy-2′-fluororibonucleoside and 5′-amino-2′,5′-dideoxy-2′α-fluororibonucleoside in succession. It was found that the introduction
