109464-23-5Relevant articles and documents
Synthesis of oligodeoxyribonucleoside methylphosphonates containing 2- aminopurine
Zhou, Yuanzhong,Ts'o, Paul O. P.
, p. 1635 - 1648 (2007/10/03)
Oligodeoxyribonucleoside methylphosphonates containing multiple 2- aminopurine bases were synthesized by solid-phase phosphonamidite chemistry for investigating their triple helix formation with natural DNA or other duplex targets and for cellular uptake studies of the methylphosphonate oligomers. The base-labile phenoxyacetyl group was used as the N2-amino protecting group for 2-aminopurine, allowing the final deprotection of the oligomers to be performed under the standard ehtylenediamine condition.