109481-85-8Relevant academic research and scientific papers
Novel building blocks: 1-Aryl-2-chloro-1-ethoxyethenes - Preparations and transformations
Yoshimatsu, Mitsuhiro,Sakai, Miho,Moriura, Eri
, p. 498 - 507 (2008/02/06)
We described here a simple method for the preparation of 1-aryl-2-chloro-1-ethoxyethenes 2a-u, which are prodrugs for Alzheimer's disease, by the reaction of dichloroacetaldehyde diethyl acetal with various aryl and alkenyllithium compounds in high yields. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
EQUILIBRIA INVOLVING HEMIKETAL AND KETAL FORMATION FROM 2-HALOGENOACETOPHENONES
Toeke, Laszlo,Keglevich, Gyoergy,Petnehazy, Imre,Szoelloesy, Aron
, p. 103 - 110 (2007/10/02)
1H-, 13C-NMR, GC measurements and some preparative work have been made to determine the hemiketal and ketal concentrations in mixtures of alcohols and 2-halogenoacetophenones.Equilibrium values for these products, as well as the time required to reach the equilibrium in the absence of acid, were found to be surprisingly high.Comparisons of the values with those of chloroacetone have also been accomplished.
