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Usage

Uses

Used in Pharmaceutical Industry:
(1E,4E)-1-(Dimethylamino)-5-(2-furyl)penta-1,4-dien-3-one is used as a building block in the synthesis of organic compounds for its potential pharmaceutical applications. Its structural features, such as the presence of a furan ring and a dimethylamino group, contribute to its biological activity, making it a promising candidate for the development of new drugs.
Additionally, it may be used as a precursor for the preparation of pharmaceuticals or agrochemicals, given its potential to be further modified or combined with other compounds to create new molecules with desired properties.
Further research and evaluation of its properties and potential applications are necessary to fully understand the significance of (1E,4E)-1-(Dimethylamino)-5-(2-furyl)penta-1,4-dien-3-one and its potential impact on the pharmaceutical and agrochemical industries.

Upstream product

• 623-15-4 4-(furan-2-yl)but-3-en-2-one 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 623-15-4 (E)-4-(furan-2-yl)but-3-en-2-one 

Relevant academic research and scientific papers

Regioselective Formal [4 + 2] Cycloadditions of Enaminones with Diazocarbonyls through RhIII-Catalyzed C-H Bond Functionalization

A regioselective formal [4 + 2] cycloaddition for the assembly of highly functionalized benzene rings was successfully developed. In this reaction, olefinic C-H bond functionalization/cyclization cascade reaction followed by rearomatization led to the desired molecules in one step under mild reaction conditions. This protocol also displays a broad substrate scope and good tolerance to a wide range of functional groups. Additionally, the potential utility for the synthesis of highly conjugated polybenzenes and diversification of natural products was also demonstrated.

Studies with enaminones: Reactivity of 1,5-disubstituted-1,4-pentadien-3-ones toward electrophilic reagents. A novel route to azolylazines, benzofuranals, pyranones

Several new enaminodienones prepared from substituted acetone and dimethylformamide dimethylacetal were used as precursors for synthesis of pyridines, pyranones and benzofurans.