1094853-97-0Relevant academic research and scientific papers
MANASSANTIN COMPOUNDS AND METHODS OF MAKING AND USING SAME
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Page/Page column 29-34, (2010/07/10)
Provided are manassantin compounds and methods of using the compounds. Provided are methods of treating a disease, the method comprising administering a compound according to Formula I. Further provided are pharmaceutical compositions comprising compounds
Nucleophilic addition of organozinc reagents to 2-sulfonyl cyclic ethers: stereoselective synthesis of manassantins a and B
Kim, Hyoungsu,Kasper, Amanda C.,Moon, Eui Jung,Park, Yongho,Wooten, Ceshea M.,Dewhirst, Mark W.,Hong, Jiyong
supporting information; experimental part, p. 89 - 92 (2009/06/28)
A convergent route to the synthesis of manassantins A and B, potent inhibitors of HIF-1, is described. Central to the synthesis is a stereoselective addition of an organozinc reagent to a 2-benzenesulfonyl cyclic ether to achieve the 2,3-cis-3,4-trans-4,5
