109503-29-9Relevant academic research and scientific papers
Ni-Catalyzed Dual C-H Annulation of Benzimidazoles with Alkynes for Synthesis of π-Extended Heteroarenes
Qi, Shao-Long,Li, Yue,Li, Jiang-Fei,Zhang, Tao,Luan, Yu-Xin,Ye, Mengchun
, p. 4034 - 4039 (2021)
Transition metal catalyzed dual C-H activation and annulation with alkynes was an attractive protocol to construct polycyclic π-extended structures. However, most of them were dominated by noble metal catalysts. Disclosed herein was the study of base-metal Ni-catalysis for dual C-H annulation of N-aromatic imidazole, which produced a range of desired polycyclic aza-quinolines in 48-95% yields. The use of bifunctional phosphine oxide ligand proved to be critical for success.
Continuous synthesis and use of N-heterocyclic carbene copper(I) complexes from insoluble Cu2O
Opalka, Suzanne M.,Park, Jin Kyoon,Longstreet, Ashley R.,McQuade, D. Tyler
supporting information, p. 996 - 999 (2013/04/10)
It is demonstrated that homogeneous N-heterocyclic carbene-copper(I)- chloride complexes can be prepared continuously by flowing NHC precursors through a packed bed of solid Cu2O suspended in molecular sieves. The method enables the synthesis o
